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, ? , , -, , , , 2 3 ? (HCV) . + ± (DCV + SOF ± RBV) / (VEL / SOF) ± RBV 2 3 , . C ( ) 2 3. () 5400 , DCV + SOF ± RBV VEL / SOF ± RBV, , . 2 DCV + SOF (94,5%) VEL / SOF (94,4%) DCV + SOF + RBV (88,1%) VEL / SOF + RBV (89,5%). 3 SVR DCV + SOF (90,8%) VEL / SOF (92,0%) DCV + SOF + RBV (88,1%) VEL / SOF + RBV (86,4%). 2 3, . 3 ( 0,51, 95% CI 0,360,72; p 3,25 (OR 0,60; 95% CI 0,43 0,84; ?= 0,002) ( 0,68; 95% 0,470,98; ?= 0,04). 2 3, VEL / SOF ± RBV, 89% 85% 12- . DCV + SOF ± RBV 56% 20% 2 HCV 12- 24- ; 53% 23% 3 12 24 , 24 . , 2 3 , DCV + SOF ± RBV VEL / SOF ± RBV , . 3 . 2 () 94%, 3 - 90%. , / . . , .
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